OPTN

 

 
 
 
Protein:  Optineurin Biological process:  Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
Molecular class:  Transcription regulatory protein Cellular component:  Perinuclear region; Cytoplasm; Nucleus
Links:  HPRD:  03891  Ensembl:  ENSG00000123240   Entrez Gene:  10133  HGNC:  17142  OMIM:  602432
 
 
 
 
Protein isoform(s) :
Low High
 
   
Protein length: 577 AA; Protein coverage: 78 %

MSHQPLSCLT EKEDSPSEST GNGPPHLAHP NLDTFTPEEL LQQMKELLTE NHQLKEAMKL NNQAMKGRFE ELSAWTEKQK EERQFFEIQS
K
EAKERLMAL SHENEKLKEE LGKLKGKSER SSEDPTDDSR LPRAEAEQEK DQLRTQVVRL QAEKADLLGI VSELQLKLNS SGSSEDSFVE
IR
MAEGEAEG SVKEIKHSPG PTRTVSTGTA LSKYRSRSAD GAKNYFEHEE LTVSQLLLCL REGNQKVERL EVALKEAKER VSDFEKKTSN
RSEIETQTEG STEKENDEEK GPETVGSEVE ALNLQVTSLF KELQEAHTKL SEAELMKKRL QEKCQALERK NSAIPSELNE KQELVYTNKK
LELQVESMLS EIK
MEQAKTE DEKSKLTVLQ MTHNKLLQEH NNALKTIEEL TRKESEKVDR AVLKELSEKL ELAEKALASK QLQMDEMKQT
IAKQEEDLET MTILR
AQMEV YCSDFHAERA AREKIHEEKE QLALQLAVLL KENDAFEDGG RQSLMEMQSR HGARTSDSDQ QAYLVQRGAE
DRDWR
QQRNI PIHSCPKCGE VLPDIDTLQI HVMDCII

 

 
 
 
Fetal heart  
Fetal liver  
Fetal gut  
Fetal ovary  
Fetal testis  
Fetal brain  
Adult frontal cortex  
Adult spinal cord  
Adult retina  
Adult heart  
Adult liver  
Adult ovary  
Adult testis  
Adult lung  
Adult adrenal gland  
Adult gallbladder  
Adult pancreas  
Adult kidney  
Adult esophagus  
Adult colon  
Adult rectum  
Adult urinary bladder  
Adult prostate  
Placenta  
B cells  
CD4+ T cells  
CD8+ T cells  
NK cells  
Monocytes  
Platelets