SPG11

 

 
 
 
Protein:  Spastic paraplegia 11 (autosomal recessive) Biological process:  Biological_process unknown
Molecular class:  Unclassified Cellular component:  Cytosol; Perinuclear region; Nucleolus; Endoplasmic reticulum; Mitochondrion
Links:  HPRD:  07963  Ensembl:  ENSG00000104133   Entrez Gene:  80208  HGNC:  11226  OMIM:  610844
 
 
 
 
Protein isoform(s) :
Low High
 
   
Protein length: 2443 AA; Protein coverage: 19 %

MAAEEGVASA ASAGGSWGTA AMGRVLPMLL VPVPAEAMGQ LGSRAQLRTQ PEALGSLTAA GSLQVLSLTP GSRGGGRCCL EGPFWHFLWE
DSRNSSTPTE KPKLLALGEN YELLIYEFNL KDGRCDATIL YSCSREALQK LIDDQDISIS LLSLRILSFH NNTSLLFINK CVILHIIFPE
RDAAIRVLNC FTLPLPAQAV DMIIDTQLCR GILFVLSSLG WIYIFDVVDG TYVAHVDLAL HKEDMCNEQQ QEPAKISSFT SLKVSQDLDV
AVIVSSSNSA VALNLNLYFR QHPGHLLCER ILEDLPIQGP KGVDEDDPVN SAYNMKLAKF SFQIDRSWKA QLSSLNETIK NSKLEVSCCA
PWFQDILHLE SPESGNHSTS VQSWAFIPQD IMHGQYNVLQ KDHAKTSDPG RSWKIMHISE QEEPIELKCV SVTGFTALFT WEVERMGYTI
TLWDLETQGM QCFSLGTKCI PVDSSGDQQL CFVLTENGLS LILFGLTQEE FLNRLMIHGS ASTVDTLCHL NGWGRCSIPI HALEAGIENR
QLDTVNFFLK SKENLFNPSS KSSVSDQFDH LSSHLYLRNV EELIPALDLL CSAIRESYSE PQSKHFSEQL LNLTLSFLNN QIKELFIHTE
ELDEHLQKGV NILTSYINEL RTFMIKFPWK LTDAIDEYDV HENVPKVKES NIWKKLSFEE VIASAILNNK IPEAQTFFRI DSHSAQKLEE
LIGIGLNLVF DNLKKNNIKE ASELLKNMGF DVKGQLLKIC FYTTNKNIRD FLVEILKEKN YFSEKEKRTI DFVHQVEKLY LGHFQENMQI
QSFPRYWIKE QDFFKHKSVL DSFLKYDCKD EFNKQDHRIV LNWALWWDQL TQESILLPRI SPEEYKSYSP EALWRYLTAR HDWLNIILWI
GEFQTQHSYA SLQQNKWPLL TVDVINQNTS CNNYMRNEIL DKLARNGVFL ASELEDFECF LLRLSRIGGV IQDTLPVQNY KTKEGWDFHS
QFILYCLEHS LQHLLYVYLD CYKLSPENCP FLEKKELHEA HPWFEFLVQC RQVASNLTDP KLIFQASLAN AQILIPTNQA SVSSMLLEGH
TLLALATTMY SPGGVSQVVQ NEENENCLKK VDPQLLKMAL TPYPKLKTAL FPQCTPPSVL PSDITIYHLI QSLSPFDPSR LFGWQSANTL
AIGDAWSHLP HFSSPDLVNK YAIVERLNFA YYLHNGRPSF AFGTFLVQEL IKSKTPKQLI QQVGNEAYVI GLSSFHIPSI GAACVCFLEL
LGLDSLKLRV DMKVANIILS YKCRNEDAQY SFIRESVAEK LSKLADGEKT TTEELLVLLE EGTWNSIQQQ EIKRLSSESS SQWALVVQFC
RLHNMKLSIS YLRECAKAND WLQFIIHSQL HNYHPAEVKS LIQYFSPVIQ DHLRLAFENL PSVPTSKMDS DQVCNKCPQE LQGSKQEMTD
LFEILLQCSE EPDSWHWLLV EAVKQQAPIL SVLASCLQGA SAISCLCVWI ITSVEDNVAT EAMGHIQDST EDHTWNLEDL SVIWRTLLTR
QKSKTLIRGF QLFFKDSPLL LVMEMYELCM FFRNYKEAEA KLLEFQKSLE TLNTAATKVH PVIPAMWLED QVCFLLKLML QQCKTQYELG
KLLQLFVERE HLFSDGPDVK KLCILCQILK DTSIAINHTI ITSYSIENLQ HECRSILERL QTDGQFALAR RVAELAELPV DNLVIKEITQ
EMQTLK
HIEQ WSLKQARIDF WKKCHENFKK NSISSKAASS FFSTQAHVAC EHPTGWSSME ERHLLLTLAG HWLAQEDVVP LDKLEELEKQ
IWLCRITQHT LGRNQEETEP RFSRQISTSG ELSFDSLASE FSFSKLAALN TSKYLELNSL PSKETCENRL DWKEQESLNF LIGRLLDDGC
VHEASRVCRY FHFYNPDVAL VLHCRALASG EASMEDLHPE IHALLQSAEL LEEEAPDIPL RRVHSTSSLD SQKFVTVPSS NEVVTNLEVL
TSKCLHGKNY CRQVLCLYDL AKELGCSYTD VAAQDGEAML RKILASQQPD RCKRAQAFIS TQGLKPDTVA ELVAEEVTRE LLTSSQGTGH
K
QMFNPTEES QTFLQLTTLC QDRTLVGMKL LDKISSVPHG ELSCTTELLI LAHHCFTLTC HMEGIIRVLQ AAHMLTDNHL APSEEYGLVV
RLLTGIGRYN EMTYIFDLLH KKHYFEVLMR KKLDPSGTLK TALLDYIKRC RPGDSEKHNM IALCFSMCRE IGENHEAAAR IQLKLIESQP
WEDSLKDGHQ LKQLLLKALT LMLDAAESYA KDSCVRQAQH CQRLTKLITL QIHFLNTGQN TMLINLGRHK LMDCILALPR FYQASIVAEA
YDFVPDWAEI LYQQVILKGD FNYLEEFKQQ RLLKSSIFEE ISKKYKQHQP TDMVMENLKK LLTYCEDVYL YYKLAYEHKF YEIVNVLLKD
PQTGCCLKDM LAG

 

 
 
Fetal heart  
Fetal liver  
Fetal gut  
Fetal ovary  
Fetal testis  
Fetal brain  
Adult frontal cortex  
Adult spinal cord  
Adult retina  
Adult heart  
Adult liver  
Adult ovary  
Adult testis  
Adult lung  
Adult adrenal gland  
Adult gallbladder  
Adult pancreas  
Adult kidney  
Adult esophagus  
Adult colon  
Adult rectum  
Adult urinary bladder  
Adult prostate  
Placenta  
B cells  
CD4+ T cells  
CD8+ T cells  
NK cells  
Monocytes  
Platelets